Search results for "corneal nerve"

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Structural, ultrastructural, and morphometric study of the zebrafish ocular surface: a model for human corneal diseases?

2018

Purpose: A morphological and morphometric study of the adult zebrafish ocular surface was performed to provide a comprehensive description of its parts and to evaluate its similarity to the human. Materials and Methods: The eyes of adult zebrafish were processed for light, transmission and scanning electron microscopy, and for immunohistochemical stain of corneal nerves; a morphometric analysis was also performed on several morphological parameters. Results: The corneal epithelium was formed by five layers of cells. No Bowman’s layer could be demonstrated. The stroma consisted of lamellae of different thickness with few keratocytes. The Descemet’s membrane was absent as the flat and polygon…

0301 basic medicineBowman's layer; corneal nerves; Descemet's membrane; ocular surface; Zebrafish; Ophthalmology; Sensory Systems; Cellular and Molecular NeuroscienceConjunctivaCorneal StromaBiologycorneal nerveCorneal DiseasesCornea03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineMicroscopy Electron TransmissionCorneamedicineAnimalsHumansTrigeminal NerveBowman MembraneZebrafishDescemet MembraneZebrafishTrigeminal nerveocular surfaceBowman’s layerCorneal DiseasesEndothelium CornealEpithelium CornealDescemet’s membraneEpithelial CellsAnatomybiology.organism_classificationSensory SystemsDescemet's membraneOphthalmology030104 developmental biologymedicine.anatomical_structureModels Animal030221 ophthalmology & optometryUltrastructureMicroscopy Electron ScanningGoblet CellsBowman MembraneConjunctivaCurrent eye research
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Short-Term Impact of FS-LASIK and SMILE on Dry Eye Metrics and Corneal Nerve Morphology

2020

PURPOSE To analyze the short-term (up to 1 month) clinical outcomes in patients undergoing corneal laser refractive surgery and the impact on dry eye disease (DED) metrics and corneal nerves using in vivo confocal microscopy (IVCM). METHODS The unaided distance visual acuity, corrected distance visual acuity, and spherical equivalent refraction (SEQ) were determined in 16 and 13 patients undergoing FS-LASIK and SMILE, respectively. DED metrics assessed were Ocular Surface Disease Index, Dry Eye Questionnaire 5-items (DEQ-5), tear film osmolarity, tear meniscus height, noninvasive keratograph breakup time (NIKBUT), ocular staining, and meibomian gland atrophy. An automated analysis of cornea…

AdultMalemedicine.medical_specialtyTime FactorsVisual acuitygenetic structuresCorneal nervemedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityMeibomian glandKeratomileusisRefraction OcularCornea03 medical and health sciencesNerve Fibers0302 clinical medicineAtrophyRefractive surgeryOphthalmologymedicineHumansOcular Surface Disease IndexProspective StudiesMicroscopy Confocalbusiness.industryLASIKmedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structure030221 ophthalmology & optometryDry Eye SyndromesFemaleLasers Excimersense organsmedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesCornea
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